Polynucleotides are regenerative skin injectables derived from purified DNA fragments that stimulate tissue repair, reduce inflammation and deeply hydrate the skin. I most commonly use Nucleofill, a clinically developed formulation designed to improve skin quality by encouraging fibroblast activity and cellular renewal. They support skin’s natural healing and rejuvenation processes.

Nucleofill is a versatile treatment that can be used on multiple areas of the face and body, including the under-eye area (tear troughs), cheeks and jawline, neck and décolletage, hands and arms, and even the scalp for hair rejuvenation.

Polynucleotides offer a wide range of regenerative benefits. They help to improve skin texture, elasticity and hydration by supporting the skin’s natural repair processes. Over time they can reduce the appearance of fine lines, improve skin tone and strengthen fragile or crepey areas, particularly under the eyes. They have anti-inflammatory properties making them ideal for skin in need of recovery and long term support.

Polynucleotides are ideal for those looking to improve skin quality at a deeper, more regenerative level. They’re particularly well suited to delicate areas, such as the under eyes, where the skin is thinner and more prone to volume loss or shadowing. This treatment is ideal for sensitive, environmentally damaged skin as well as anyone seeking longer term support for hydration, healing and cellular renewal.

After cleansing and preparing the skin, a series of small injections are placed just beneath the surface of the skin in targeted areas using a very fine needle. The treatment is well tolerated, though you may experience stinging and slight swelling at the injection site, particularly the under eye area. There’s minimal downtime. Results develop over a couple of weeks, with a course of treatments recommended for optimal, longer-lasting results.